Chapter: MOLECULAR BASIS OF INHERITANCE
BIO XII 2.2.1 A
Q.1. What are three components of nucleotides.
Q.2. How nucleotide differs from a nucleoside?
Q.3. Write Chargaff's rules of base pairing.
Q.4. Draw double helix model of DNA and write its dimensions also.
Q.5. Briefly describe (in points) the salient features of Double helix model of DNA proposed by Watson and Crick.
Q.6. Write the central dogma in molecular biology. why it is named so?
Q.7. How chromatin differs from DNA?
Q.8. What is a nucleosome? Name the proteins which constitute histone octamers?
Q.9. What are properties of histone protein?
Q.10.Differentiate between Heterochromatin and Euchromatin.
Q.11.Explain how chromatin forms chromosomes?
Q.12.Draw structure of a typical chromosome and label various parts.
Q.13.Define transformation. Who discovered it?
Q.14.Briefly describe transformation experiment by Griffith.( Flow Chart Only)
Q.15.Describe briefly the the procedure and findings of exp[eriment performed by Avery McLeod and McCarty.
Q.16.How did Harshey and Chase prove that DNA is the genetic material?
Q.17.What is the crtiteria which must be fulfilled by a molecule acting as genetic material?(4 points)
Q.18.Why DNA is a better genetic material as compared to RNA? (4 Points)
make a list of functions/roles performed by RNA.
Q.19.Draw structure of tRNA molecule and label it.
Q.20.What is replication?
Q.21.Why DNA replication is called semi conservative? Who discovered this?
Q.22.What are three types of RNA? Write their functions also.
Q.23.Make a list of enzymes involved in replication and write functions of each enzyme.
Q.24.Briefly explain the mechanism of DNA replication in steps.
Q.25.Describe the following terms: Ori site Leading or continuous strand lagging or discontinuous strand okazaki fragments.
Q.26.Draw Schematic diagram of transcriptional unit and label it.
Q.27.With the help of diagrams show show following steps of transcription in prokaryotes:
Initiation Elongation Termination
Q.28.With the help of diagram show RNA splicing, Capping and tailing takes place in eukaryotes?
Q.29.What is the difference between hnRNA and mRNA?
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